Abstract

Objective: The Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial found that dual-chamber pacing (DDDR-70) at rates of 70 beats/min or faster in patients with standard indications for an implantable defibrillator but no indication for pacing increased the risk of death or hospitalization for congestive heart failure (CHF). It was not possible to determine from the DAVID trial whether this harm resulted from a faster heart rate from pacing or specifically from the location in the heart where pacing was conducted.

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