Abstract
In this study, the impact of anatomical changes on radiation dose variations of the prostate and bladder (as an organ at risk) was assessed for a potential scenario of magnetic resonance imaging-guided carbon-ion radiotherapy (MRgCT) of prostate cancer. To achieve this goal, carbon-ion beams perpendicular to a pelvis phantom affected by 1.5 T perpendicular magnetic field were simulated using the FLUKA code. Prostate diameter change from 6 to 1 cm leads to a prostate dose reduction of 88%. Bladder diameter change from 10 to 5 cm leads to a reduction of 92% in bladder dose. The set-up error of 5 mm leads to a decrease of 5% in the prostate dose. Rectum diameter change from 5 to 3 cm leads to reductions of 20% and 26% in prostate and bladder dose, respectively. In conclusion, anatomical changes impact on dose variations in MRgCT of prostate cancer.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have