Abstract

Although post-menopausal obesity is an important public national health problem in Saudi Arabia, to date no study has evaluated the effects of weight reduction on biochemical & clinical parameters and quality of Life for obese Saudi post-menopausal women. The aim of this study was examine the effects of aerobic versus resisted exercise training effects upon systemic inflammation biomarkers and quality of life for obese post-menopausal Saudi women. One hundred Saudi post-menopausal obese women participated in this study, their age ranged from 50-58 years and their body mass index (BMI) ranged from 30-35 kg/m2. All participants were divided into two equal groups: The first group received aerobic exercise training on treadmill where, the second group received resisted exercise training. Health-related quality of life (SF-36 HRQL), tumor necrosis factor- alpha(TNF-α), Interleukin-2(IL-2), Interleukin-4 (IL-4), Interleukin-6 (IL-6) and C-reactive protein (CRP) were measured before and after 3 months at the end of the study. The mean values of SF-36 HRQL subscale scores were significantly increased, while the mean value of TNF-α, Il-2, IL-4, IL-6, CRP and BMI were significantly decreased in both groups after treatments. There were significant differences between mean levels of the investigated parameters in group (A) and group (B) after treatment with more changes in patients received aerobic exercise training. The current study provides evidence that aerobic exercise is more appropriate than resisted exercise training in modulating inflammatory cytokines and quality of life among obese post-menopausal women.

Highlights

  • Post-menopausal women, especially those with body mass index (BMI) greater than 30 kg/m2, have lower health-related quality of life (HRQOL) in physical functioning, energy, and vitality compared with normal-weight women[1]

  • A review of 8 studies examining HROQL among women aged over 55 years old concluded that post-menopausal women, especially those with BMI greater than 30 kg/m2, have lower HRQOL in physical functioning, energy, and vitality compared with normal-weight women[1]

  • Our findings were consistent with several studies have shown that exercise intervention might enhance health-related quality of life and psychological well-being[24,25,26,27,28,29,30,31] as Teomana et al enrolled 81 volunteer post-menopausal women who have been taking hormone replacement treatment (HRT) were divided randomly into two groups: exercise group and control group

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Summary

Introduction

Post-menopausal women, especially those with body mass index (BMI) greater than 30 kg/m2, have lower health-related quality of life (HRQOL) in physical functioning, energy, and vitality compared with normal-weight women[1]. A review of 8 studies examining HROQL among women aged over 55 years old concluded that post-menopausal women, especially those with BMI greater than 30 kg/m2, have lower HRQOL in physical functioning, energy, and vitality compared with normal-weight women[1]. Objective: The aim of this study was examine the effects of aerobic versus resisted exercise training effects upon systemic inflammation biomarkers and quality of life for obese post-menopausal Saudi women. Conclusion: The current study provides evidence that aerobic exercise is more appropriate than resisted exercise training in modulating inflammatory cytokines and quality of life among obese post-menopausal women.

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