Abstract

Background: Concurrent chemoradiotherapy (CCRT) plus intracavitary brachytherapy (ICBT) is standard of care for locally advanced cervical cancer (LACC). However, because of differences in tissue response and anatomy, brachytherapy sometimes fails to deliver adequate doses and may result in higher recurrence rates. Thus, there have been studies discussing the role of adjuvant hysterectomy (AH). National Comprehensive Cancer Network cervical guidelines (NCCN ver. 2022.1) listed AH as an option after CCRT when patient has bulky tumor, disease extended or poor response to CCRT. The purpose of this study was to analyze the impact of AH on bulky cervical cancer patients after CCRT with insufficient brachytherapy dose.

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