Abstract

The novel coronavirus disease 2019 (COVID-19) was characterized as a global pandemic by the World Health Organization (WHO) on March 11, 2020. The present pandemic has caused an intolerable impact on the health structure as well as the pharmaceutical sector, which in ultimatum has created enormous issues in the everyday lives of the patient community. On the other hand, the situation may appear in short and long-term time-horizon and need identification along with appropriate planning to reduce their socio-economic burden. The Indian pharmaceutical industry is the world's third-largest drug producer by volume. India supplies affordable and low-cost generic drugs to millions of people around the globe and operates more than 250 United States Food and Drug Administration (USFDA) and United Kingdom Medicine and Healthcare products Regulatory Agency (UKMHRA) approved plants. Given the Indian pharmaceutical industry, the source of Active Pharmaceutical Ingredients (APIs) for multiple diseases is much crucial part of the Pharma industry’s strategic plan to combat the COVID-19 pandemic. China is the top global producer and exporter of APIs by volume and Indian pharmaceutical industries are also rely heavily on APIs from China for the production of their medicine formulations by importing around 70 percent of the total requirement. However, the present pandemic situation has exposed the world's over-reliance on China in terms of API import and bound world leaders to fig. out sustainable alternatives.

Highlights

  • The review of literature related to the present systematic review study was carried out in the period from April 2020 to October 2020

  • The shipments of drugs like paracetamol, erythromycin salts, Vitamins B1, B6, and B12, acyclovir, and progesterone were only allowed to import with a no-objection certificate (NOC) that companies claimed were difficult to procure. This was around the time that Wuhan province in China, from where these Active Pharmaceutical Ingredients were mostly imported, was under a strict COVID-19 pandemic lockdown

  • As various countries are willing to invest in the Indian market for the supply of COVID-19 vaccine and medical equipment, this is the chance for India to become truly self-reliant in the pharmaceutical segment [36]

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Summary

Introduction

The review of literature related to the present systematic review study was carried out in the period from April 2020 to October 2020. Active Pharmaceutical Ingredients (APIs) means the effective ingredient which is contained in the medicine. The world is in an alarming situation amid the pandemic coronavirus disease and due to which it has been shown that there is a huge scarcity regarding APIs which are very much integral parts to make medicine or medical products [3, 4].

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