Abstract
Purpose: Studies of runners indicate that an increased rate of vertical loading during the initial contact phase of gait is associated with an increased risk of running-related knee pain, a finding that has prompted testing of specialized shoes and gait retraining interventions to reduce injury risk. Comparable studies are lacking in non-running populations that are at-risk for OA-related knee pain. Studies comparing loading rates across different individuals are challenged by the need to control for confounding by between-person differences in age, sex, body mass, race, and in particular, footwear and walking velocity.
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