Abstract
IntroductionThe objective was to compare incidence rates of whooping cough in children under the age of 1 in Castelló, before and after the introduction of vaccination of pregnant women in January 2015. MethodsThe incidence of the POST-vaccine period (2015-2018) was compared with the PRE-vaccine period (2011-2014) in all ages, in children from 3 to 11 months and under 3 months. The relative risks (RR) and their 95% confidence intervals were calculated. ResultsThe overall rate of pertussis in all ages was higher in the POST-vaccine period (0.23 per 1000 person-years) than in the PRE-vaccine period (0.15), but decreased in those under 3 months. The RR were: 1.56 (1.34 – 1.82) in all ages; 1.73 (0.87-3.57) for children aged 3 to 11 months, and 0.35 (0.16-0.69) for children under 3 months. A similar pattern was observed for hospitalised children. ConclusionsThe incidence rate in children under 3 months was reduced by 65% in the period after the intervention, the hospitalisation risk rate by 71%, suggesting that the measure has been effective and specific for this age group.
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