Abstract
Cystic fibrosis (CF) is the commonest life-threatening inherited condition in the UK, affecting more than 6000 people at the present time. Advances in all aspects of clinical management, in particular early treatment of pulmonary infections and attention to nutrition, have contributed to a significant improvement in prognosis, with a current median age of survival of 30 years. There is increasing evidence that early intervention after establishing the diagnosis in asymptomatic patients has numerous medical, psychological and financial benefits. Neonatal screening programmes have been available in some populations since 1980 and in view of the benefits discussed below should play an integral part in the management of CE
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