Abstract
Estimates of the fraction of human malignancies that are associated with viral infections range from 10% to 20% (1). Among viruses and their associated cancers are Epstein-Barr virus (EBV), which is associated with many different malignant diseases including lymphoproliferative disease (LPD) in immunosuppressed patients, Hodgkin’s disease, Burkitt’s lymphoma and nasopharyngeal carcinoma; human papillomaviruses (HPV) types 16 and 18 with cervical cancer; hepatitis B (HBV) and hepatitis C viruses with hepatocellular carcinoma; human T-cell leukemia virus-1 with adult T-cell lymphoma; and human herpes virus-8 with Kaposi’s sarcoma in patients with AIDS.
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