Abstract
A number of excellent reviews on the potential of canine cancer immunotherapy are available, but many extrapolate from observations in humans when in fact only very few immunotherapies have been developed for canines that have shown efficacy in well-designed studies. Pharmaceutical and biotech companies are aware that the market for more expensive immunotherapies in canines is limited resulting in limited funding for clinical trials. However, dogs and other pets deserve access to this new form of cancer therapy. The purpose of this brief review is to summarize the current status of available immunotherapies for dogs and their near-term prospects, provided we can effectively translate discoveries and progress in humans to canines.
Highlights
Hans Klingemann*A number of excellent reviews on the potential of canine cancer immunotherapy are available, but many extrapolate from observations in humans when only very few immunotherapies have been developed for canines that have shown efficacy in welldesigned studies
Immunotherapy is the new buzzword in human oncology
Immunotherapy is not expected to become the panacea for all canine tumors – we know from human patients that some cancers respond well to immunotherapy, but solid tumors still have poor responses [3]
Summary
A number of excellent reviews on the potential of canine cancer immunotherapy are available, but many extrapolate from observations in humans when only very few immunotherapies have been developed for canines that have shown efficacy in welldesigned studies. Pharmaceutical and biotech companies are aware that the market for more expensive immunotherapies in canines is limited resulting in limited funding for clinical trials. Dogs and other pets deserve access to this new form of cancer therapy. The purpose of this brief review is to summarize the current status of available immunotherapies for dogs and their near-term prospects, provided we can effectively translate discoveries and progress in humans to canines. Austria Maciej Parys, Royal (Dick) School of Veterinary Studies, United Kingdom. Specialty section: This article was submitted to Comparative Immunology, a section of the journal
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