Immunotherapy for canine cancer

Abstract

Cancer in dogs is a serious and prevalent disease that has drawn significant attention in the field of veterinary medicine, representing the most common cause of death in adult dogs. Traditional treatments such as chemotherapy and surgery have many limitations and side effects and have not been able to completely eliminate cancer, and challenges still remain in improving the survival rate and life quality in dogs. The development of a new therapeutic methodology for canine cancer to improve treatment effectiveness and survival rate has become the focus of many scientists. Immunotherapy, as a new treatment strategy, is one of the important research directions in the field of cancer treatment in canine animals. Adoptive T-cell therapy, checkpoint inhibitors, and oncolytic virus therapy, as important immunotherapy approaches, have shown promising treatment effects. This article will introduce the background of canine cancer, the background of immunotherapy, and discuss the application prospects of adoptive T-cell therapy, checkpoint inhibitors, oncolytic virus therapy, and other related topics in the treatment of canine cancer.