Abstract
Meeting abstracts The success of antibody-based theranostics depends on the identification of tumor specific biomarkers and the development of corresponding antibodies with high-affinity and specificity. Tumor endothelial marker-1 (TEM1) is highly expressed in tumor vasculature of multiple cancers
Highlights
Chunsheng Li1*, Junying Wang1, Jia Hu1, Ann Marie Chacko2, Aizhi Zhao1, Chaitanya Divgi4, Vladimir Muzykantov3, George Coukos1
The success of antibody-based theranostics depends on the identification of tumor specific biomarkers and the development of corresponding antibodies with high-affinity and specificity
Developing sensitive and effective theranostic agents against TEM1 are of utmost significance in improving diagnosis and treatment of ovarian cancer
Summary
Chunsheng Li1*, Junying Wang1, Jia Hu1, Ann Marie Chacko2, Aizhi Zhao1, Chaitanya Divgi4, Vladimir Muzykantov3, George Coukos1. Immunotargeting of tumor vasculature: preclinical development of novel antibodybased imaging and therapy against TEM1/CD248 From Society for Immunotherapy of Cancer 28th Annual Meeting National Harbor, MD, USA.
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