Abstract
To put the subject matter of this chapter in its proper perspective, it should first be made clear that the development of a vaccine against trypanosomiasis of cattle and sheep is perhaps the last practical possibility which would occur to most people whose daily business is concerned with the control of trypanosomiasis in the field in Africa today. The simple fact is that no one has yet evolved a technique of immunization which has been clearly shown to confer a significant degree of protection to domestic animals grazing in endemic areas.
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