Abstract

Objective The purpose of this study was to evaluate the effects of Enterococcus faecalis FK-23(FK-23) on the immune function in mice. Methods Mice were treated with three doses of the FK-23(0.05, 0.1, 0.2, 0.6 g/kg body weight) for 30 days. Delayed type hypersensitivity (DTH), monocyte phagocytic function, serum hemolysis antibody and natural killer cell activity were studied. Results The significant increases in mice treated with 0.6 g/kg bw were found in DTH, phagocytic function of monocyte, serum hemolysis antibody and natural killer cell activity. Conclusion The results from the present study suggest that FK-23 could improve both specific and non-specific immune function.

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