Immuno-microbiological aspects of chronic apical periodontitis

Abstract

Event Abstract Back to Event Immuno-microbiological aspects of chronic apical periodontitis Ludmila A. Mozgovaya1, Irina I. Zadorina1, Liliya P. Bykova2 and Anatoliy P. Godovalov3* 1 Acad. E.A. Wagner Perm State Medical Academy, therapeutic dentistry, Russia 2 Acad. E.A. Wagner Perm State Medical Academy, microbiology and virology, Russia 3 Acad. E.A. Wagner Perm State Medical Academy, immunology, Russia Microbiological research of 24 root canals discharge at patients with chronic apical periodontitis was conducted. In assessing the persistence of opportunistic microbial species identified a number of cultures of obligate and facultative forms, of which dominated gram-positive species. Thus, in 62.9% of cases identified members of the genus Staphylococcus, including most types of coagulasa-positive met (St. aureus, intermedius et hyicus). In 70.4% of cases were found members of the genus Streptococcus, among which the most met Str. pyogenes and enterococci. Of gram-negative Neisseria species predominated (62.5%), the family Enterobacteriaceae (Proteus mirabilis et Citrobacter diversus) represented 25%. Growth of Lactobacillus sp. detected in 33% of cases, and Corynebacterium sp. - in 11%. Anaerobes (Prevotella, Fusobacterium, Peptococcus etc.) isolated in 29.6%. At this patients found that the total protein concentration in root canals at maximum value observed in radicular cyst and minimal - in chronic periodontitis. During exacerbation of chronic periodontitis, the total protein concentration in the discharge of the root canal rises slightly, while the number of white blood cells is significantly increased (mainly granulocytes). Thus, it can be assumed that chronic apical periodontitis is caused predominantly by bacteria of the genus Staphylococcus and Streptococcus, and chronic inflammation is supported by the presence of a number of leukocyte that produce massive amounts of protein molecules (globulin). Keywords: chronic apical periodontitis, Bacteria, white blood cells, root canals discharge, chronic inflammation Conference: 15th International Congress of Immunology (ICI), Milan, Italy, 22 Aug - 27 Aug, 2013. Presentation Type: Abstract Topic: Host-pathogen interactions Citation: Mozgovaya LA, Zadorina II, Bykova LP and Godovalov AP (2013). Immuno-microbiological aspects of chronic apical periodontitis. Front. Immunol. Conference Abstract: 15th International Congress of Immunology (ICI). doi: 10.3389/conf.fimmu.2013.02.00655 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 11 Jun 2013; Published Online: 22 Aug 2013. * Correspondence: Mr. Anatoliy P Godovalov, Acad. E.A. Wagner Perm State Medical Academy, immunology, Perm, Russia, AGodovalov@gmail.com Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Ludmila A Mozgovaya Irina I Zadorina Liliya P Bykova Anatoliy P Godovalov Google Ludmila A Mozgovaya Irina I Zadorina Liliya P Bykova Anatoliy P Godovalov Google Scholar Ludmila A Mozgovaya Irina I Zadorina Liliya P Bykova Anatoliy P Godovalov PubMed Ludmila A Mozgovaya Irina I Zadorina Liliya P Bykova Anatoliy P Godovalov Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.