Abstract
Immunological studies were performed on six patients suffering from ascaris migration into the biliary tree. Studies were performed before and after surgical exploration of the biliary tree, using skin tests, complement fixation, and hemagglutination tests. Of these, the skin test using purified ascaris antigen was found to be most sensitive. The serum IgE level increased before the operation in all six cases. After removal of the migrated ascaris at surgery, the serum IgE level decreased to normal range within one month. Prausnitz-Küstner reactions (P-K) were performed in eight healthy volunteers, using the patients' sera before and after the operation. Only sera from preoperative patients gave positive P-K reactions. These findings strongly suggest that the preoperative increase in serum IgE is attributable to the ascaris infestation. In addition, we found that the purified ascaris antigen has a high chemotactic effect on eosinophils (A-ECF). This ascaris-derived eosinophil chemotactic factor appears to differ from factors derived from complement components or lymphocytes.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
