Abstract
Antibody of restricted heterogeneity produced in high titers in response to a given antigen is commonly observed in patients affected with subacute sclerosing panencephalitis and is comparable to what is observed in rabbits hyperimmunized with bacterial vaccines. Subacute sclerosing panencephalitis immunoglobulins were isolated and partially sequenced. Their immunological activity was measured with measles virus, subacute sclerosing panencephalitis virus (LEC strain) and distemper virus.
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