Abstract
Peptic ulcer of the stomach and duodenum is a disease, the etiology of which has not been precisely established. Taking into account the chronic recurrent course of the disease, seasonality, connection with a violation of the diet, increased sensitivity to parenteral administration of protein preparations, an immunoallergic hypothesis of the pathogenesis of peptic ulcer disease was put forward [46]. In our country, it was supported by S.M. Ryss. In the modern literature, the issue of changes in the general immune status in peptic ulcer disease is widely covered.
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