Abstract
Immunological characterization of endocervical mucus in normal and neoplastic tissue.
Highlights
THE PRESENCE of tissue-specific antigen in various mucins has been demonstrated in a number of studies (Bara et al, 1977; Hillermanns, 1962; Nairn et al, 1962)
After extensive absorption, there was no significant reactivity with normal endometrium, but there was still marked fluorescence of mucus in frozen sections from endocervix (Fig. 1)
Sections of adenocarcinoma of endocervical origin (10 patients) showed bright fluorescence, whereas there was no fluorescence in sections of carcinoma of the endometrium (9 patients) (Figs 3 & 4)
Summary
THE PRESENCE of tissue-specific antigen in various mucins has been demonstrated in a number of studies (Bara et al, 1977; Hillermanns, 1962; Nairn et al, 1962). The unabsorbed serum gave bright fluorescence of frozen sections of endocervix as well as other tissues, including endometrium, Fallopian tube and colon. After extensive absorption, there was no significant reactivity with normal endometrium, but there was still marked fluorescence of mucus in frozen sections from endocervix (Fig. 1). All sections tested (13 patients) showed linear staining of the free glandular surface, with no free mucus staining (Fig. 2).
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
