Immunological Aspects of Patients Infested with Scabies in Thi-Qar Province, Southern Iraq

Abstract

Scabies is skin disease of human and many mammalian hosts caused by the important obligate parasites Sarcoptes scabiei, lives and reproduces in epidermis ,resulting a significant human and animal morbidity. The current study aimed to determine the immunological responses in patients infested with scabies who attended a private clinic in Al-Hussein general hospital in Thi-Qar province. The total white blood cell count, differential counts (lymphocytes, monocytes, neutrophils, eosinophils and basophils), the serum levels of IL-5 and IL-13 in were evaluated in all patients with scabies and compared with non-infested healthy individuals as a control group. The present study showed significant increase on the mean of total WBC in patients infested with scabies when compared with control (P? 0.05). A significant differences (P? 0.05) were recorded in the absolute leukocytes counts for patient infested with scabies when compared with control group except that for monocytes and basophils which were non significant (P? 0.05) in our study. The results of study showed significant differences (P? 0.05) in the mean of IL-5 and IL-13 serum levels for the patient infested with scabies when compared with control.