Immunologic Alterations in Long-Term Divers

Abstract

Event Abstract Back to Event Immunologic Alterations in Long-Term Divers Hassan Abolhassani1*, Asghar Aghamohammadi1, Nima Rezaei1, Khodayar Ghorban2, Banafsheh Dormanesh3 and Maryam Dadmaneh2 1 Tehran University of Medical Science, Research Center for Immunodeficiency,Children's Medical Center Hospital, Pediatrics Center of Excellence, Iran 2 AJA University of Medical Sciences, Department of Immunology, Iran 3 AJA University of Medical Sciences, Pediatric Nephrology, Iran Diving could encounter the immune system of divers due to long term stressors and disasters. This study was designed to understand comprehensive effect of diving on the cellular and humoral components of immune system in a number of persons with long-term exposures. The cross-sectional study was developed on 25-male-expert divers. The immunologic parameters were compared in these individuals with 25 sex-age-matched healthy controls. Serum levels of IgA(p<0.001)and IgM(p=0.003)were significantly decreased in divers compared to the controls; while the levels of IgG and IgE(p<0.001)were significantly increased. Absolute count of B cells was significantly lower in the divers group, compared to the controls(p<0.001). Specific-antibody-responses of divers was also defected(p<0.01).An increased activity of classic pathway of complement components was detected in the divers(p<0.001). Absolute count of natural killer cells in the divers was also significantly higher than the controls(p<0.001).Humoral, cellular and complement components of the immune system could be involved during long-term diving. Keywords: Diving, Immune function, Infection, secondary immunodeficiency, hyperbaric oxygen exposure Conference: 15th International Congress of Immunology (ICI), Milan, Italy, 22 Aug - 27 Aug, 2013. Presentation Type: Abstract Topic: Immune-mediated disease pathogenesis Citation: Abolhassani H, Aghamohammadi A, Rezaei N, Ghorban K, Dormanesh B and Dadmaneh M (2013). Immunologic Alterations in Long-Term Divers. Front. Immunol. Conference Abstract: 15th International Congress of Immunology (ICI). doi: 10.3389/conf.fimmu.2013.02.00377 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 15 Mar 2013; Published Online: 22 Aug 2013. * Correspondence: Dr. Hassan Abolhassani, Tehran University of Medical Science, Research Center for Immunodeficiency,Children's Medical Center Hospital, Pediatrics Center of Excellence, Tehran, 14194, Iran, hassan.abolhassani@ki.se Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract Supplemental Data The Authors in Frontiers Hassan Abolhassani Asghar Aghamohammadi Nima Rezaei Khodayar Ghorban Banafsheh Dormanesh Maryam Dadmaneh Google Hassan Abolhassani Asghar Aghamohammadi Nima Rezaei Khodayar Ghorban Banafsheh Dormanesh Maryam Dadmaneh Google Scholar Hassan Abolhassani Asghar Aghamohammadi Nima Rezaei Khodayar Ghorban Banafsheh Dormanesh Maryam Dadmaneh PubMed Hassan Abolhassani Asghar Aghamohammadi Nima Rezaei Khodayar Ghorban Banafsheh Dormanesh Maryam Dadmaneh Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.