Abstract
Immunohistochemical (IHC) identification of the porcine circovirus type 2 (PCV-2) in organs and tissues was applied for better diagnostics of porcine circovirus disease. The IHC provides an additional confirmation to the diagnosis and allows to access cell and tissue tropism of the virus in pig organs. The research was conducted in animal tissues obtained during the disease outbreaks in pig farms using own monoclonal antibodies to the virus capsid protein. The results of IHC study have provided an insight into etiological role of the PCV-2 in pathological lesions found in all observed parenchymal organs, most of them localized in the lungs and lymph nodes. Accumulation of the virus has been found in the alveolar macrophages and lymph nodes. The lesions detected in other parenchymal organs have not been associated with PCV-2 accumulation.
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