IMMUNOHISTOCHEMICAL MARKERS IN DIAGNOSTICS OF ORAL PRECANCEROUS DISEASES

Abstract

Over the past 15 years, the incidence of cancer of the oral cavity, pharynx, and larynx has increased by 15-17%, and almost 90% of patients are working people (30-60 years old). There were 32 patients (15 men and 17 women) aged 35 to 60 years with oral precancerous diseases examined at the department of Therapeutic Dentistry of Tashkent State Dental Institute. An IHC study in patients diagnosed with flat leukoplakia did not reveal neoplastic transformation of epithelial cells; the main changes in the epithelium were characterized by hyperplasia with cell proliferation.