Abstract
The presence of nerve growth factor (NGF)-like protein was investigated in the cochlea of the developing rat between birth and postnatal day 30, by the indirect immunofluorescence technique. Nerve growth factor-like protein could be detected from birth up to day 8. The immunostaining was localised within the hair mainly above their nuclei. No NGF-like immunoreactivity was observed in spiral ganglion cells. The data suggest that NGF acts as a neurotrophic factor, especially for efferent endings in the developing cochlea.
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