Abstract
The immunoperoxidase-immunoglobulin bridge technique was used to study the distribution of lysozyme (LZM) in the minor salivary glands and other tissues in man. Specific LZM-staining was seen in the intralobular ducts of all glands. Acinar LZM was detected in von Ebner's serous glands of the tongue, in the serous demilunes of the mixed glands and, to a considerably lesser extent, in a few pure mucous glands. As LZM was detected only in the salivary glands and, with the exception of a few resident granulocytes, monocytes and tissue macrophages, in no other tissue within the oral cavity, it is probable that salivary glands are the principal source of salivary LZM.
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