Abstract
The Bombay (Oh) phenotype is a rare phenotype in which red blood cells lack the H antigen as a result of a point mutation in the H gene. Oh patients are a challenge in transfusion medicine. We present a case of a pediatric patient with the Bombay phenotype who was carried to the emergency department of the Hospital Universitario San Vicente Fundación in Medellín, Colombia. The patient presented gastrointestinal hemorrhage and required transfusion therapy. Pretransfusion and molecular immunohematological analyses identified the Bombay phenotype. The patient was transfused with Oh red blood cells imported to Colombia from the Hematology and Hemotherapy Center of Ceará (Hemoce) in Fortaleza, Brazil. This first case of an Oh individual in Colombia highlights the need to look for donors with rare phenotypes to fulfill the transfusion requirements of the population.
Published Version
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