Abstract
In order to study on Immunoglobulin Response in pertussis were used 40 blood samples from 20 children infected with pertussis.Serological methods used for this study were Bacterial agglutination test and Sucrose density gradient centrifugation.The results obtained are summerized as followed:1. In patients, the appearance of 19S antibody was detected in 100% of the cases at the first week, and the 19S antibody persisted for long-term.2. The appearance of 7S antibody was detected later than 19S antibody, and was detected in 100% of the cases at the seventh to eighth weeks. Whereas, in reinfection, it was detected at the first week.3. The appearance of the IgA polymer followed 19S antibody, it was detected in theabout 30% of the cases at the second to sixth weeks.4. In regard to the sedimentation pattern and agglutinin titer, it was found that the agglutinin titer rose in the sequence of negative, 19S, 19S+IgA polymer, 19S>7S, 19S=7S+IgA polymer, 19S<7S.
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Schedule a callMore From: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases
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