Abstract
Immunoglobulin levels in maternal blood, cord blood and breast milk of Nigerian pregnant women using hydroquinone and non-hydroquinone containing skin lightening creams
Highlights
Skin lightening cream, refers to any substance or mixture used for the purpose of lightening the skin color
The subjects were recruited from two maternity centers in Ibadan, Nigeria. Those on special medication, history of recent blood transfusion, those with various infections, those with complicated pregnancy, those on special diet and those with pre-term delivery were excluded from the study
No statistical significant differences were observed when the mean levels of maternal IgA (246.08 ± 90.30mg/dl), cord IgA (256.21 ± 111.91mg/dl) and breast milk IgA (244.07 ± 104.08mg/dl) in users of hydroquinone containing skin lightening creams were compared with the levels of maternal IgA (253.39 ± 78.02mg/dl), cord IgA (264.74 ± 86.16mg/dl), and breast milk IgA (260.54 ± 78.98mg/dl) in users of non – hydroquinone containing skin lightening creams (p>0.05 in each case)
Summary
Refers to any substance or mixture used for the purpose of lightening the skin color. The mean levels of maternal IgA, cord IgA and breast milk IgA of the of the pregnant women using skin lightening creams were 240.02 ± 86.63mg/dl, 252.56 ± 105.16mg/dl and 236.55 ± 97.81 mg/dl respectively, while the corresponding values in the control subjects were 236.87 ± 59.53mg/dl, 238.57 ± 73.06mg/dl and 234.74 ± 79.57 mg/dl respectively.
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