Abstract
K Patel, J Akhter, L Kobrynski, MA Benjamin Gathmann, O Davis, KE Sullivan; International DiGeorge Syndrome Immunodeficiency Consortium. J Pediatr. 2012;161(5):950–953 To better characterize humoral immunity in patients with DiGeorge syndrome. An international cohort of 1023 patients with DiGeorge syndrome was used in this investigation. This included data from 21 countries and 40 different contributors, including 662 records from the US Immunodeficiency Network, 381 from the European Society for Immunodeficiencies, 327 from the Children’s Hospital of Philadelphia, and fewer than 50 patients per institution from the remaining contributors. The investigators defined a low serum immunoglobulin G (IgG) value as <500 mg/dL and a low CD3+ count as <500 cells/mm3 to stratify patients for the …
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