Abstract

Two blood plasma lipoprotein allotypes are described. Specific antiallotypic reagents were obtained from alloimmune precipitating sera produced against normal plasma and subsequently against lipoprotein fractions of d<1.072 g/ml. Identification studies by means of centrifugation and specific staining show that Lcp1 and Lcp2 are markers of the low-density liproprotein class, 1.006<d<1.063 g/ml. Serological and genetic studies indicate that the two alloantigens behave as products of allelic genes, each occuring with varying frequencies in 20 lines studied. The Lcp1 antigen is always accompanied by Lcp2; however, the latter was also found to occur in plasma of birds lacking the Lcpl marker.

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