Abstract
Parallel quantitative estimation of antibodies to Candida albicans group A in serum and saliva was carried out in controls, carriers and infected subjects, using the indirect immunofluorescent technique. Antibodies were demonstrated in serum and saliva. Controls gave titres in serum up to 1:8, and in saliva up to × 64 concentrated saliva. Carriers showed levels in serum up to 1:16, and up to × 16 in concentrated saliva. Candidiasis patients had serum titres up to 1:512, and salivary titres up to 1:8. Thus, the three groups differed quantitatively in their immunological status. A serum titre of 1:32 or above, and a saliva titre of 1:1 or above therefore indicates clinical infection, and so aids in the differential diagnosis of candidiasis.
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