Abstract

Antigens synthesized in LLC-MK 2 cells infected with SA7 were described using indirect immunofluorescence. When cells were reacted with sera from tumor-bearing hamsters, “T” antigens were observed as early as 10 hr post-infection (PI). In certain cells a second type of exclusively intranuclear fluorescence was observed at 16 hr PI. Specific antiviral sera reacted with viral structural antigens approximately 15–16 hr PI. Sera from hamsters immunized with density gradient-purified virus reacted with both “T” antigens and viral antigens.

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