Abstract
To examine the cytochemical features of primary vestibular afferent neurons, we examined the immunocytochemical distribution of substance P(SP) and neurofilament proteins (NFP) in the guinea pig vestibular endorgans and ganglion. 84.9% of vestibular ganglion cells showed SP-like immunoreactivity. SP immunoreactive cells were small in diameter (25.4 microns), and randomly distributed in the ganglia. NFP immunoreactive cells (34.2%) were relatively large in diameter (31.1 microns). By double-staining immunocytochemistry it was possible to distinguish three different cell types: SP-positive/NFP-negative, SP-negative/NFP-positive, and SP/NFP-positive vestibular ganglion cells. Vestibular ganglion cells can thus be classified on the basis of size and immunocytochemical characteristics. These chemically distinct subpopulations of vestibular ganglion cells may be an indication of functional differences within vestibular afferent neurons.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
