Abstract
A method of immunochromatographic assay for rapid detection of human heart-type fatty acid-binding protein (h-FABP) as an early marker of acute myocardial infarction was developed. Gold nanoparticles were used as a visual label. The optimum conditions for assay were determined. The limit of detection in the assay was 1.5 ng/mL, and the variation coefficient did not exceed 8%. Using the developed test system, the clinical diagnosis of acute myocardial infarction (N = 10) was confirmed, and the results of testing the serum of healthy individuals (N = 25) were negative.
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