Abstract
1. 1. 6-Phosphogluconate dehydrogenase (6PGD) activity and electrophoretic mobility were investigated in red cells of fourteen mammalian species. 2. 2. The comparative antigenic structure of 6PGD of various species was investigated by immunodiffusion with antisera prepared against non-hemoglobin protein fraction of human and bovine erythrocytes, coupled with a specific chromogenic reaction. 3. 3. Two common antigenic determinants were detected in 6PGD of representatives of primates, Bovidae and Equidae families. 4. 4. Only one of these determinants was found in the enzymes of members of Canidae and Caviidae families. 5. 5. The anti-human serum revealed also an antigenic determinant specific to 6PGD of man and Cercopithecidae, while the anti-bovine serum revealed an antigenic determinant specific to the Bovidae family. 6. 6. Two variants of human 6PGD (PDG A/PGD C and PGD C/PGD C) produced on immunodiffusion reactions of complete identity with the usual phenotype (PGD A/PGD A).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Comparative Biochemistry and Physiology -- Part B: Biochemistry and Molecular Biology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
