Abstract

Summary The bactericidal action of human serum against V. comma, strain 82, is a result of the combined action of antibody and complement. The bactericidal action of human complement against this vibrio is destroyed by the inactivation of any one of the four complement components. Such a complement is said to be specifically inactivated. Bactericidal action is restored to a specifically inactivated complement (siC′) by the addition to it of the particular complement component which it lacks. Bactericidal action of human complement against this vibrio is fortified in particular by the addition of the “pH=5.4—μ 0.02 supernate.” All evidence in this paper points to the identity of bactericidal and hemolytic complements in human serum.

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