Abstract
1. 1. The presence of met- and leu-enkephalin-like immunoreactive materials in nerve, gut, seminal vesicle and body wall tissues of the earthworm Lumbricus terrestris has been demonstrated by means of radioimmunoassay technique. 2. 2. The greatest activity of met- and leu-enkephalin-like immunoreactivity in earthworm gut appears in regions of high digestive enzyme activity and gastrin-like immunoreactivity where it presumably plays a role in regulation of gut function. 3. 3. In all tissues studied the levels of met-enkephalin-like immunoreactivity were higher than that of leu-enkephalin-like immunoreactivity. 4. 4. Dual localization of met- and leu-enkephalin-like immunoreactivity in earthworm gut and nerve tissues follows the pattern observed of peptide hormones in vertebrates which are common to both endocrine and non-endocrine tissues.
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