Abstract
The involvement of autoimmune processes in certain ophthalmologic diseases has long been discussed by many investigators. Recently, D'Ermo 1 has further stressed the potential importance of autoimmune phenomena in pathological conditions of the lens. It is generally agreed that the injection of heterologous or homologous lens extracts evokes the production of circulating antibodies, a conclusion which has been extensively documented in the recent review of Halbert and Mansky. 2 However, the demonstration of antibody formation following the injection of autologous lens antigens is less readily achieved. Muller 3 reported that simple trauma of the lens in rabbits induced an immune response, but these results were not confirmed in the experiments of Lyda and Lippincott. 4 However Uhlenhuth and Handel 5 also succeeded in demonstrating autoimmunization of guinea pigs with lens material. More recently Hackett and Thompson 6 detected antibodies to lens extracts in the sera of many healthy humans, and
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
