Immunization against cow's milk in infants with cleft lip and/or palate

Abstract

70 pg/day) for 10 days from 8 to 17 November. Abdominal distention and pain increased markedly. Watery diarrhoea contaminated with fresh blood developed on 11 November. Plain abdominal radiograph showed marked dilatation of the small intestine. Computed tomography on 13 November showed thickening of the intestinal wall but no pneumatosis. A diagnosis of neutropenic enterocolitis was made. Intravenous hyperalimentation was instituted. No neutrophils were found in the peripheral blood count until 16 November when they increased to 0.33 x 109/1. Fever disappeared 2 days later. On 24 November, neutrophils reached 1 • 109/I and examination of iliac bone marrow showed complete remission. Computed tomography on 28 November showed normal intestinal wall size. The mainstay of treatment for neutropenic enterocolitis is an appropriate use of antibiotics and careful regulation of water and electrolyte balance until the return of functioning neutrophils. In our patient rG-CSF treatment was initiated 2 days after development of profound neutropenia. Though there was no dramatic response, the favourable course is slightly suggestive of a positive effect of rG-CSF.