Abstract
Summary The immunity of the newborn infant to certain diseases is passive in character and is soon replaced by susceptibility more marked than that of older individuals. This great susceptibility may account for many of the unusual characteristics of disease in infancy and is dependent apparently on a deficiency in the capacity of the infant to produce antibodies. This deficiency requires that more intensive therapy be applied toward infectious disease in infancy wherever such therapy is available, e.g., as in serum treatment of pneumonia. Also the inadequate antibody response in early infancy should lead to delay in the active immunizations at least until the second half year of life when passive immunity derived from the mother has been lost and immunizability of the infant is rising.
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