Abstract
Galectin-3 is a β-galactoside-binding animal lectin that contains carbohydrate-recognition domains and displays multiple related functions. It has important roles in diverse biological events, such as embryogenesis, growth, cell adhesion, proliferation, differantiation, cell-cycle progression, apoptosis, mRNA splicing, and regulation of the immune system. Galectin-3 is expressed in various cells and tissues, such as activated macrophages, eosinophils, neutrophils, mast cells, epithelium of the gastrointestinal and respiratory tracts, kidneys and some sensory neurons, and is also involved in tumorigenesis, angiogenesis, and tumor metastasis. In this review of the literature, immunohistochemical Galectin-3 expression is investigated in numerous tumors and disorders of various organ systems.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
