Abstract

Immune-endocrine cross-talk in reproductive biology and pathology.

Highlights

  • Immune system and local immune regulations earn a prominent role in the coordination of those processes

  • A proper fetomaternal immune-endocrine cross-talk during early pregnancy is fundamental for reproductive success

  • Maj and coworkers address the regulation of peripheral tolerance of maternal immune system during pregnancy establishment

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Summary

Introduction

Editorial Immune-Endocrine Cross-Talk in Reproductive Biology and Pathology Regulation of the reproductive function in mammals is a very complex biological process, tightly coordinated by the interplay between hypothalamic-pituitary axis and gonads. A myriad of factors regulates both estrous cycle and pregnancy, through the in situ activation of molecular pathways that coordinate subsequent cellular changes.

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