Abstract
Juvenile idiopathic arthritis is a disease characterized by autoimmune disorders and immune imbalance.In recent years, immune tolerance has become a hot issue in the pathogenesis of juvenile idiopathic arthritis.In this article, cytotoxic T lymphocyte associated-antigen 4, programmed death-1, Treg cells and apoptotic cells in the pathogenesis of juvenile idiopathic arthritis are summarized. Key words: Juvenile idiopathic arthritis; Immune tolerance
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