Abstract
The article presents a comparative analysis of immunity indicators in the lactating cows with subclinical mastitis, after treatment with the ointment Uberosept and in combination with the drugs containing interferons. It has been found that treatment regimens using the immunomodulatory drugs Submastin KRS and Mixoferon lead to an increase in the serum bactericidal and lysozyme activity. The number of total immunoglobulins increased significantly. Moreover, after the course of treatment, a decrease in the number of circulating immune complexes was noted, which indicated a decrease in the antigenic load and partial release from microorganisms that cause mastitis. In experimental groups No. 2 and No. 3, there was a tendency towards a decrease in phagocytic activity, phagocytic index and phagocytic number, which indicated the stage of recovery. When comparing two treatment regimens with interferoncontaining drugs, it was noted that in the experimental group in which “Mixoferon” was used, a more pronounced immunostimulating effect was observed.
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