Abstract
Modern clinical observations focused on the increasing complications at the open mandible fracture, which indicated about severe immune suppression in patients with this pathology. For estimation cellular immunity in a peripheral blood there were examined 25 patients in basic group (15 men, 10 women) with mandible fracture, complicated with abscess of a bone wound; control group included 20 practically healthy persons (10 men and 10 women). To assess cellular immunity in the peripheral blood were determined: absolute number of leukocytes, relative amount of lymphocytes; phagocytic activity. Determination relative number of T–lymphocytes (phenotype CD2+, СD3+) and B – lymphocytes (phenotype СD22+) was performed by method of immunofluorescence with monoclonal antibodies. In a case of mandible fracture, complicated with abscess of bone wound and leukocytosis, in the patients were reduced parameters of cellular immunity: on 40.3% – phagocytic index, on 47.7% – phagocytic number, on 43.9% – content of CD2+– and CD3+– lymphocytes. Content of null cells was increased on 76.8 %
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