Abstract

The study was carried out to determine the humoral immune response to Newcastle Disease Virus (NDV) and Bangladesh Agricultural University Fowl cholera (BAUFC) vaccines in Shuvra chicken, a newly develop chicken strain by BLRI (Bangladesh Livestock Research Institute). Ten Shuvra chickens were vaccinated with Baby Chick Ranikhet Disease Vaccine (BCRDV) at day 7 through intra ocular route (i/o) and with Ranikhet Disease Vaccine (RDV) at day 35 through intramuscular (i/m) route. Vaccine induced serum Haemagglunination Inhibition (HI) antibodies were measured by HI test. Two weeks after final immunization all vaccinated and control Shuvra chickens were challenged with virulent field isolates of NDV where all the vaccinated birds survived without showing any typical signs of NDV during the period of ten days observation period and all the control chickens died. Another 10 Shuvra were vaccinated twice with BAUFC vaccine through intramuscular route at day 42 and 70, and 10 Shuvra chickens were kept as unvaccinated control. This vaccine also induced significantly higher level of antibody titre as determined by Passive Haemagglutination (PHA) test. Vaccinated chickens showed significantly higher survival (80%) following challenge with virulent fowl cholera isolate and all the control birds died within 10 days of observation period. DOI: http://dx.doi.org/10.3329/bjvm.v10i1-2.15639Bangl. J. Vet. Med. (2012). 10 (1&2): 1-7

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