Abstract
Henoch Schonlein purpura (HSP) is a multiple immune mediated systemic immune vasculitis with an immune complex characterized by deposition of small blood vessels in the affected tissue. HSP complex etiology, infection, food and drugs can cause disease. Its exact pathogenesis is still not clear, may be related to abnormal immune functions, IgA immune complex deposition, T lymphocyte dysfunction, abnormal lymphocyte activation, B interleukin (IL) -17, IL-21, IL-6, visfatin, IL-8 secretion, and intestinal mucosal barrier dysfunction and so on. Key words: Henoch-Schonlein purpura; Immunology; Intestinal mucosal barrier function; Pathogenesis
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