Abstract
The UC and Crohn's disease are chronic, idiopathic, inflammatory diseases of the GIT that share common symptoms such as diarrhea, abdominal pain, fever, and weight loss. Ulcerative colitis involves all or part of the colon, whereas, Crohn's disease commonly involves the terminal ileum and proximal colon. The two major forms of IBD share many clinical and epidemiological characteristics, suggesting that underlying causation may be similar. Yet, UC & Crohn's disease are distinct syndromes with divergent treatment and prognosis. Aim of the study: Study a relationship between some parasitic infections such as helminthes infestation, and the development of IBD. Understanding the correlation between parasitic infections and autoimmune disorders may be helpful in prediction, early identification and conceivably the prevention of these diseases. The current study also showed immunological evidence that helminthes can modulate host immune response to prevent and minimize the inflammatory response in cases of IBD through increasing the level of anti-inflammatory cytokines and decreasing the level of pro-inflammatory cytokines. The combined infestation with multiple intestinal helminthes has a better protective role than single parasite in protection against inflammatory bowel disease.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Indian Journal of Forensic Medicine & Toxicology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
