Abstract
Hepatitis B virus (HBV) and Hepatitis C virus (HCV) are the major causes of chronic liver inflammation worldwide. Although both viruses induce immune-mediated acute and chronic inflammatory liver diseases, the natural history and outcome of HBV and HCV infections are different. This is because of both viruses and host features, like genetic, immunologic and environmental. Hereby, we present the immune mechanisms and immunopathogenesis involved in chronic viral hepatitis. Keywords: HBV, HCV, Innate immunity, Adaptive immunity
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