Immune function varies with reproductive stage and context in female and male tree lizards, Urosaurus ornatus

Abstract

Competition among physiological processes for limited resources often results in trade-offs. Key among these processes is reproduction and immune function, and optimizing both appears to be difficult. To test the hypothesis that the resource demands of reproduction compromise immune function, we measured rates of wound healing, an integrated measure of innate immunity, across different reproductive stages in female and male tree lizards ( Urosaurus ornatus) in both the field and the laboratory. The hypothesis predicted that immune function would be lowest when resource demands of reproduction are highest, i.e., vitellogenic females and reproductive males. In the field, vitellogenic females had significantly slower healing rate than females in other reproductive stages. However, in the laboratory, vitellogenic females had a healing rate similar to that of other females. Conversely, males showed suppression of healing in the laboratory but not in the field during the reproductive season. The results of this study support a trade-off between reproduction and immune function, and suggest that reproduction is given priority. However, the results also indicate that this trade-off is not fixed in the reproductive process and that it may instead be dependent on the context, sex or resource balance of the individual.